All work

Case study 03 · Data integration · Trial oversight

Clinical Operations & Supply Command Center

One internal site for both of our trials. It pulls RTSM, EDC, depot and compassionate use data in automatically, and replaces the weekly clinical trial meeting deck with live meeting pages.

Role
Designed and built end to end
Built with
Next.js and TypeScript on Azure, with Microsoft sign-in and a secure drop folder for vendor data, written with Claude Code
Setting
Crossbow Therapeutics, two Phase 1 trials and a compassionate use program
Status
Live for both trials

The tool · click through the pages

Illustrative data, not from a live study

Command Center

Overview

ABC-101

Phase 1 · relapsed/refractory multiple myeloma

5

On treatment

14 discontinued

3

Screening

1 screen failed

9 / 10

Sites active

DEF-202

Phase 1 · metastatic castration-resistant prostate cancer

3

On treatment

1 discontinued

1

Screening

0 screen failed

5 / 7

Sites active

Patients dosed over time

Cumulative C1D1 from RTSM · both studies

27

patients dosed

24 +1 last 30 days

ABC-101

3 +1 last 30 days

DEF-202

Compassionate use

ABC-101 compassionate use · from CU lists

3

Active patients

5

Patients on list

1

Pending approvals

  • SC

    CU-01 · Site 203 · Myeloma

    C1D1 2 Mar 2026 · latest 6 mg/kg · C1D8

    Discontinued
  • SC

    CU-02 · Site 204 · Myeloma

    C1D1 1 Apr 2026 · latest 10 mg/kg · C4D1

    On treatment
  • IV

    CU-04 · Site 201 · Myeloma

    Not yet dosed

    Submitted to FDA
  • SC

    CU-05 · Site 204 · Myeloma

    Not yet dosed

    Local IRB approved

The problem

Hours of manual work every week to build one deck

Every week, enrollment, dispensing and inventory reports had to be downloaded from the EDC, the RTSM and the drug depot, analyzed by hand and rebuilt into slides. Two trials meant twice the work.

It took 6 to 10 hours a week, and the finished deck was still only a snapshot, often out of date by the time the meeting started.

What I built

Both trials, live, on one site

  1. 01

    Automated data feeds

    RTSM, EDC and depot reports land daily in a secure folder and are read automatically. Compassionate use records come straight from SharePoint.

  2. 02

    One view of both trials

    Patients, cohorts, drug supply and sites for both studies, with every number traced to its source file and timestamp.

  3. 03

    Meeting pages, not slides

    Data sections fill themselves. Each function updates its own section, which carries forward week to week until someone reviews it.

  4. 04

    Finalize and archive

    Finalizing the week freezes the record and archives a PowerPoint in the company template. Every edit is versioned and audited.

Results

What changed

  • Saves 6 to 10 hours of manual work every week
  • Used by clinical operations, regulatory, quality, CMC, clinical supply and executive leadership
  • Replaces the weekly clinical trial meeting deck
  • Removes manual data pulls from RTSM, EDC and the drug depot
  • Tracks both trials and the compassionate use program in one place

Next case study

Clinical Supply Planner